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Psychedelic drugs—also known as hallucinogens—are substances that alter perception, mood, consciousness, and sensory awareness. These drugs can dramatically change how you think, feel, and experience your environment. Psychedelics include both synthetic hallucinogens (such as LSD and MDMA) and naturally occurring psychedelics (such as psilocybin mushrooms and mescaline from peyote cactus).
Common Types of Psychedelic Drugs
Some of the most widely used psychedelic substances include:
Psychedelics work by altering neurotransmitter activity—primarily serotonin, dopamine, and glutamate. These neurotransmitters regulate:
By binding to serotonin (5-HT2A) receptors, psychedelics can create a state of neuroplasticity, increasing sensory awareness, emotional openness, creativity, and altered thinking.
This heightened brain connectivity is why psychedelics are being studied for potential therapeutic use—but it also increases the risk for psychological distress, bad trips, and long-term mental health complications.
Psychedelics affect each person differently. Common short-term effects include:
Psychedelics are generally considered less physically addictive than substances like opioids, alcohol, or stimulants. However, behavioral addiction and psychological dependence can still occur—especially when psychedelics are used:
Repeated psychedelic use can also lead to tolerance, meaning higher doses are needed to feel the same effects—a major risk factor for problematic use.
You may benefit from psychedelic addiction treatment if you notice:
If any of these resonate, it’s important to consult a mental health or addiction specialist.
When speaking with a doctor or therapist about psychedelic misuse, consider asking:
While psychedelics don’t cause physical withdrawal like opioids or alcohol, psychological symptoms can be severe and require professional treatment.
Available treatment levels include:
If you have symptoms of depression, anxiety, PTSD, or psychosis, look for a rehab offering dual diagnosis treatment.
Evidence-based treatments may include:
Combined, these therapies help you regain control, reduce cravings, and process emotional issues that may contribute to psychedelic misuse.
Supportive resources include:
If you feel out of control, overwhelmed, or concerned about your use, reaching out is the first step toward healing.